2026
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We develop innovative synthetic strategies at the interface of organoboron chemistry, strained-ring chemistry, photoredox catalysis, and chemical biology to enable the efficient synthesis and late-stage functionalization of pharmaceuticals and other biologically active molecules.
Research
The development of innovative synthetic methodologies is fundamental to expanding the chemical space accessible for the construction of structurally diverse and functionally complex molecules. Our research focuses on developing modern synthetic strategies by harnessing the unique reactivity of organoboron compounds, strained-ring systems, and photoredox catalysis to enable the efficient synthesis and late-stage functionalization of complex and biologically relevant molecules.
2026
2026
Org. Lett. (2026) 28 (32): 10397–10402
Stereospecific Strain-Release-Driven Ring Opening of Azabicyclo[1.1.0]butanes to Access N-β-Substituted Chiral Azetidines
2026
Org. Lett. 2026, 28, 2012–2017.
Strain-Release Asymmetric Multicomponent Reaction to Access Diverse N-α-Bisaryl-C3-quaternary Azetidines
2026
Nat Commun 2026, 17, 2695
Late-stage N-Me selective alkenylation and alkynylation of drugs and unactivated tertiary amines using photoredox catalysis
2026
Angew. Chem. Int. Ed., 2026, 65, e20548.
Catalytic & Enantioselective Ring Opening of Azabicyclo[1.1.0]Butyl Carbinols via N-Allylation of Strained Tertiary Amines
2025
Nat Commun, 2025, 16, 8679.
HFIP-assisted Brønsted acid-catalyzed ring opening of 1-azabicyclo[1.1.0]butane to access diverse C3-quaternary aza-azetidines and indole-azetidines
Lab archive
Research Publications
Our publications highlight advances in synthetic organic chemistry, with a focus on organoboron chemistry, strained-ring chemistry, photoredox catalysis, and late-stage functionalization. They reflect our efforts to develop innovative methodologies for the synthesis of complex and biologically relevant molecules.
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Leadership
Prof. S. Panda
Associate Professor, Department of Chemistry, IIT Kharagpur
Prof. Santanu Panda is an Associate Professor in the Department of Chemistry at IIT Kharagpur. Prof. Santanu Panda leads the research group at IIT Kharagpur, focusing on innovative synthetic methodology, organoboron chemistry, strained-ring chemistry, photoredox catalysis, and…
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